Regenerative Treatment

Polynucleotides

One of Miss Naji's most favoured treatments for its regenerative properties. Polynucleotides are the building blocks of DNA and RNA, injected to improve skin quality, complexion and appearance from within.

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Polynucleotides treatment
Duration
15-30 mins
Pain Level
Mild
Results
2-8 weeks
Results Last
3-6 months
Price
From £375

What Are Polynucleotides?

Polynucleotides (PN) are chains of nucleotides derived from Salmon Trout DNA. When injected, they stimulate fibroblast activity, boost collagen and elastin production, and improve the skin’s ability to retain moisture.

The treatment works at a cellular level. Unlike fillers which add volume, polynucleotides actually improve the quality and structure of the skin itself. Results build gradually and can last up to 12 months.

This treatment

Stimulates collagen and elastin

Improves skin hydration from within

Reduces fine lines and crepey texture

Promotes tissue regeneration

Suitable for face, neck, hands, and scalp

Treatment Areas

Polynucleotides For

For Skin

Improve thin, crepey, pigmented, or aged skin anywhere on the body. Most effective around the eyes, polynucleotides thicken the skin itself, enhancing radiance and reducing fine lines.

From £375
15-30 mins
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For Hair

Stimulate dormant hair follicles and improve scalp health. Polynucleotides promote blood flow and deliver regenerative properties, resulting in thicker, stronger and more resilient hair growth.

From £375
15-30 mins
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For Intimate Areas

A specialised regenerative treatment that improves tissue elasticity, tone and quality, reducing symptoms of dryness and discomfort while improving satisfaction.

From £375
15-30 mins
Book a Consultation
Results

Before & After

Signs of Ageing
Pictures Courtesy of Dr. A Law, Plinest, DermaFocus
Hair Loss
Pictures Courtesy of Mastelli, Plinest Hair, DermaFocus
Smoker's Lines
Pictures Courtesy of Dr. A Law, Plinest, DermaFocus

The images above show genuine, unedited outcomes shared with patient consent. Individual results depend on skin type, treatment plan, and adherence to aftercare advice.

Patient Feedback
★★★★★
5.0 from 9 Google reviews
★★★★★

I am currently undergoing a treatment journey with Dr Shetha for my acne scarring using Sofwave. I had my first treatment last week, and Dr Shetha couldn't have made me feel more at ease and reassured during the session. She made sure to explain everything throughly, and go at my pace when it got a bit spicy! I am already receiving compliments on my skin, which has boosted my confidence. This is just the start of my skin journey with Dr Shetha, and I can't wait to see my full results down the line. If you are looking for a safe and reliable practitioner, you can't find better than Dr Shetha. She cares about her patients before anything! Looking forward to returning for my next treatment.

Jemima Duncombe
3 weeks ago
★★★★★

Shetha was so friendly and reassuring, and she really took the time to explain everything clearly, including all the options. Her surgical expertise really shone through, even in the non-invasive treatment I had, which gave me total confidence knowing I was in expert hands. Her medical background really sets her apart, I’d highly recommend this clinic!

Sehlina Osei-Baidoo
9 months ago
★★★★★

A lovely experience and would highly recommend. Shetha is very skilled and gentle and makes you feel welcome the moment you step through the door. Again, highly recommend. Her knowledge is second to none and her treatments embody this.

Rebecca Osei-Baidoo
9 months ago
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Sourced from Google Reviews
Common Questions

Frequently Asked Questions

Polynucleotides are an incredible example of regenerative medicine and, in fact, can be a preventative aging treatment. They may be used to improve the quality of skin in both younger and more mature patients. They can improve thin, crepey, pigmented, or aged skin anywhere on the body, while improving skin plumpness and turgor.

In addition to evening pigmentation of the skin, they are effective in the treatment of scarring, including acne scarring and striae, due to their promotion of cell turnover, accelerated wound healing and collagen stimulation.

Most effective around the eyes, polynucleotides increase volume by thickening the skin itself, enhancing skin radiance and reducing fine lines and wrinkles.

Polynucleotides can be used with and without non-crossed linked hyaluronic acid to further increase skin hydration and plumpness, depending on the treatment area and skin needs.

Polynucleotides can also be used to treat thinning hair by stimulating follicles and improving scalp microcirculation. They also have anti-inflammatory properties, which result in thicker, stronger and more resilient hair growth.

For maturing women, vulvo-vaginal tissues also suffer from the aging process, where collagen and elastin levels decline. This can lead to loss of tone and elasticity, dryness, itch and discomfort.

Polynucleotides, just like in cutaneous skin, stimulate fibroblasts when injected into intimate areas to yield similar results in terms of improved tissue elasticity, tone and quality, which leads to the reduction of symptoms while offering a non-hormonal, minimally-invasive treatment option. Clinical evidence has shown polynucleotides are thus able to improve sexual satisfaction.

This truly regenerative medical treatment is ideal for improving the quality of your skin and tissues and can be used alongside most treatments to enhance the overall outcome.

Polynucleotides transform your skin quality, tone and firmness from within. They stimulate fibroblasts, leading to increased collagen and elastic production, accelerated wound healing and regeneration, and reduced inflammation. The result is intense hydration, restored elasticity, and plumper, healthier skin. In turn, this smooths fine lines, reviving dull, tired skin and improving pigmentation. With its effect on collagen remodelling, polynucleotides can improve scar quality and appearance.

Polynucleotides have been used for more than 30 years and have a good safety profile. The polynucleotides used by Miss Shetha Naji are derived from rainbow salmon trout in Italy. The purification process is such that even patients with fish allergies are able to use these products.

As with any medical treatment, there are potential side effects, but these are rare. Most side effects are related to the administration method, i.e. the injection, which can cause bleeding, pain, bruising or swelling. However, these effects are temporary and typically resolve within a few days. Various administration methods are used for different areas and will be discussed with you prior to any treatment performed.

You will meet our plastic surgery consultant, Miss Shetha Naji, for a face-to-face consultation. You will have a full medical and aesthetic consultation detailing your desires and concerns, and following a thorough and systematic assessment, a treatment plan will be devised. This will include a detailed explanation of the procedure itself, associated risks and aftercare. There is no obligation to undertake any treatment.

If you wish to proceed, the treatment will typically last no longer than 30 minutes. Local anaesthetic (topical/injected) is used prior to the treatment to minimise discomfort.

Some swelling, redness and bumps may be visible following the treatment. Depending on the administration method, this may typically take 2-5 days to settle. Specific post-procedure advice depends on the area treated, but downtime is minimal.

We do advise against having any aesthetic treatments immediately prior to any formal or significant event.

A follow up appointment in person is not typically required following the injection of polynucleotides, but if desired, a follow up consultation may be held.

Ideally, polynucleotides are used as a course of treatments as they effect the new growing skin cells that emerge during the skin cycle. The length of the skin cycle increases as we age and results vary. Typically, we advise that you will not see results of the treatment for a minimum of six weeks.

Everyone is unique, and the length of time for which the results of a polynucleotides lasts also depends on which area of the body is treated. For hair, the results can last up to two months, while for skin and intimate areas the results may last up to six months or longer.

Start Your Journey

Book Your Consultation

Every treatment plan begins with a thorough, one-to-one consultation. Miss Naji will assess your needs and create a personalised approach, with no obligation to proceed.